Prostatic Stromal Hyperplasia with Atypia

Prostatic Stromal Hyperplasia with Atypia

Prostatic stromal hyperplasia with atypia (PSHA) is a rare histologic finding diagnosed incidentally on prostate biopsies, transurethral resection specimens, and radical prostatectomy specimens. PSHA has a bizarre histologic appearance and these lesions often raise concern for sarcoma; however, their clinical course is indolent and does not include extraprostatic progression. We discuss a case ...

Androgen Receptor Expression in Epithelial and Stromal Cells of Prostatic Carcinoma and Benign Prostatic Hyperplasia

BACKGROUND Prostatic carcinoma (PCa) derives from prostatic epithelial cells. However stromal microenvironment, associated with malignant epithelium, also plays a role in prostatic carcinogenesis. Alterations in prostatic stromal cells contribute to the loss of growth control in epithelial cells that lead to progression of PCa. AIM To analyse the differences between Androgen Receptor (AR) exp...

Benign prostatic hyperplasia.

Benign prostatic hyperplasia.

This article reviews the epidemiology of benign prostatic hyperplasia (BPH), evaluation of patients with lower urinary tract symptomatology (LUTS), and management of patients with BPH and LUTS. The evaluation includes history and physical examination, laboratory testing, and specialized studies. The management includes medical and surgical options. Medical options include alpha-1-adrenergic rec...

Benign Prostatic Hyperplasia

Urinary obstruction as a result of benign prostatic disease has probably been recognized to some degree since the earl iest days of medicine. This association was probably f irst formalized by Riolan in the seventeenth century. In the mideighteenth century, Morgagni (248) provided one of the earl iest descriptions of BPH and enumerated many of the potential medical problems attendant to its dev...